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2012 January-March

Vol 2 Issue 1

12. Review Articles
Title:Twin Studies: Revealing the Genetic Basis of Malocclusion
Author(s):Dolly P Patel, Bhaskar Gupta, Tanmay Sharma


The relative contribution of genes and the environment to the etiology of malocclusion has been a matter of controversy throughout the twentieth century and the first decace of twentyfirst century. Twin studies provide important insights into how genetic and environmental factors contribute to variation in dental and craniofacial morphology. This review describes research models involving twins, apart from the traditional comparison of similarities in monozygotic (identical) and dizygotic (nonidentical) pairs, throws some light on zygosity determination, summarizes some landmark twin studies in orthodontics and future directions in dental research involving twins are outlined.

Keywords:Twins, Twin studies, Heredity, Zygosity determination, Monozygotic and Dizygotic.

How to Cite: Patel DP, Gupta B, Sharma T. Twin Studies: Revealing the Genetic Basis of Malocclusion. J Orofac Res 2012;2(1):48-51.

Source of support: Nil

Conflict of interest: None declared

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